
The GOLD Standard For Skin Rejuvenation & Hair Revitalization


The Science of Exosomes
Our bodies replace, repair, and renew their cells. They work by creating and exporting
healing molecules that are packaged into special carriers called exosomes.
Exosomes are small vesicles that are secreted by cells into the extracellular
environment. They are formed within the endosomal compartment of the cell and are
typically 30-150nm in diameter.
Exosomes are involved in intercellular communication and carry a variety of molecules,
such as lipids, RNAs, growth factors, cytokines, and other functional proteins.
They play an important role in cell-to-cell signaling and immune responses. They
represent a promising area of research with evolving applications in regenerative
medicine, aesthetics, and as a potential delivery system for therapeutics.
What Can Exosomes Do?
- Skin, Scalp & Hair Rejuvenation.
- Reduce Downtime and Post Inflammatory Response from Aesthetic Medical Treatments.
- Enhance Product Penetration.
- Assist in Retaining Skin Moisture, Promotes Hydration.
- Stimulate Collagen Production.
- Supports Tissue Repair.
- Brighten and Even Skin Tone.

Advancing Regenerative Biotherapeutics
Leading Manufacture, Researcher and Product Development
Age Zero™ Prue Exosomes
Xolence Biotherapeutics manufactures Age Zero™ Pure Exosomes in our cGMP facility, register with the FDA
HCT/P establishment, and licensed by New York State as a NYS tissue bank. We process under ISO 5 Certified
BSL2 hoods and ISO 9001:2015 Compliance.
They are acellular, preservative-free, and manufactured with Xeno-Free, Serum-Free media. Twenty percent
of every lot manufactured is sent for sterility, endotoxin, and environmental testing by a third-party C.L.I.A.
Certified laboratory that is a global leader in pharmaceutical, cosmetic, and environmental testing.
We package and ship in multi-use, frozen vials stable for six months @ -20C. We are registered as a cosmetic
with the FDA MoCRA and actively distribute in the USA, Canada, UAE, Qatar, Turkey, Lebanon, Pakistan, and
Azerbaijan.

Age Zero™ Pure Exosomes
- Wharton’s Jelly (MSC’s) Mesenchymal Stem Cells
- Low Passage (4)
- Immune Privileged
- Pure Exosomes, Highest Potency
- Acellular
- Biologically Active, Gold Standard
- Frozen, Never Lyophilized
- Suspended in Clinical Grade Saline
- Counted and Characterized
- Manufactured in cGMP Facility
- American Donors Screened & Tested
- CLIA Certificate of Conformity & Safety
Clinical Trial Results
100 Participants
3 Trial Arms: 5, 50 or 100 Billion
Age Zero Exosomes Topically + Microneedling
Treatment Day 0, Day 30 and Day 60